For Those With HIV, Hep C Drug Trials Don’t Offer Enough Real-World Data

February 22, 2016 The major clinical trials of hepatitis C virus (HCV) drugs among those coinfected with HIV had such restrictive eligibility requirements, their findings’ generalizability is questionable. Publishing their findings in Clinical Infectious Diseases, researchers looked at 541 HIV/HCV-coinfected members of the Canadian Coinfection Cohort with genotypes 1 through…

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Baraclude as Hep B Therapy Doesn’t Work as Well in the Real World

February 24, 2016 A look at Baraclude (entectavir) as treatment for hepatitis B virus (HBV) in real-world settings found the drug was safe and effective, but not as effective as in clinical trials. Publishing their findings in Alimentary Pharmacology & Therapeutics, researchers conducted a retrospective cohort study of 658 people…

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AbbVie Hep C Regimen Clashes With Some HIV Protease Inhibitors

February 16, 2016 The evening dose of AbbVie’s hepatitis C virus (HCV) treatment Viekira Pak (ombitasvir/paritaprevir/ritonavir; dasabuvir) may interact harmfully with HIV protease inhibitors (PIs), Medscape reports. Publishing their findings in Clinical Infectious Diseases, researchers conducted five Phase I, multiple-dose, open-label pharmacokinetic studies among 144 HIV-negative volunteers. The participants were…

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326 cases of Hepatitis C traced in 3 years

February 8, 2016 A large number of cases of Hepatitis C are being traced in the blood bank during blood donation. Except for a survey conducted at a village in the district, there has been no assessment over the matter. However, the health authorities are of view that in every…

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FDA expands use of BMS’ hepatitis C drug

February 8, 2016 The US Food and Drug Administration has expanded the approved uses for Bristol-Myers Squibb’s Daklinza to include three new subsets of difficult-to-treat patients with hepatitis C (HCV). The regulator has cleared the drug’s use, in combination with sofosbuvir (Gilead’s Sovaldi, with or without ribavirin) in HCV patients…

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CDC Warns of New Cases of Hepatitis C Among Those on Dialysis

February 8, 2016 The Centers for Disease Control and Prevention (CDC) has warned of growing reports of new cases of hepatitis C virus (HCV) among individuals receiving dialysis, MedPage Today reports. Publishing an announcement on its website, the health agency said it had received reports of 36 cases of acute,…

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